联系方式

职  称:副教授

所在部门:生命分析化学与原子分子工程研究所

研究方向:结合等温核酸扩增技术、毛细管电泳技术建立高灵敏、高通量检测生物标志物研究

办 公 室 :

联系电话:

电子邮件:zhanghuige@lzu.edu.cn

张会鸽,讲师,女,1981年10月生。2003年本科毕业于兰州大学化学化工学院分析化学专业。2003年至2008年,在兰州大学化学系分析化学专业攻读博士学位(硕博连读)。2010年9月起在兰州大学化学化工学院工作。主持和完成国家自然科学基金青年基金项目和两个“中央高校基本科研业务费”项目。目前主要研究兴趣包括:解决与发展生物标志物高灵敏度检测为目标,围绕其基本原理、检测方法、展开了系统而深入的研究;构建可视化检测方法、基于荧光识别的检测技术;结合毛细管电泳方法,建立高通量、高灵敏检测生物标志物的分析方法。

国家自然科学青年基金1项:

名称:基于适配体等多重链替代扩增-毛细管电泳高通量检测低丰度蛋白质新技术   (主持)

中央高校基本科研业务费2项:

名称:选择性磁性纳米碳真的合成及其在提高毛细管电泳检测灵敏度中的应用;(主持)

名称:基于适配体的链替代扩增技术可视化检测地风度蛋白质 (主持)


1. Wei Chen; Huige Zhang; Yanning Zhang; Meiyi Hui; Hongli Chen; Cuiling Ren; Duolong Di; Haixia Zhang; Construction of dual exponential amplification accompanied by multi-terminal signal output method for convenient detection of tumor biomarker FEN1 activity, Analytica Chimica Acta, 2023, 1263.

2. Huige Zhang; Zixi Gao; Fei He; Jingfeng Lan; Hailong Chai; Shiqian Zhang; Xianwei Zuo; Hongli Chen; Xingguo Chen; Generation of 3′-OH terminal–triggered encoding of multicolor fluorescence for simultaneous detection of different DNA glycosylases, Analytical and Bioanalytical Chemistry, 2022, 414: 6989-7000.

3. Huige Zhang; Fengyun Li; Lili Wang; Shuai Shao; Hongli Chen; Xingguo Chen; Sensitive homogeneous fluorescent detection of DNA glycosylase by target-triggering ligation-dependent tricyclic cascade amplification, Talanta, 2020, 220: 121422

4. Huige Zhang; Lili Wang; Yi Xie; Xianwei Zuo; Hongli Chen; Xingguo Chen; Base excision repair mediated cascading triplesignal amplification for the sensitive detection of human alkyladenine DNA glycosylase, analyst, 2019, 144: 3064-3071.

5. Huige Zhang; Li-juan Wang; Lili Wang; Hongli Chen; Xingguo Chen; Chun-yang Zhang; Development of a cascade isothermal amplification approach for the sensitive detection of DNA methyltransferase, Journal of Materials Chemistry B, 2018, 7: 157-162.

6. Huige Zhang, Fengyun Li, Yanhua Ma, Shengda Qi, Xingguo Chen, Lei Zhou. AuNPs colorimetric sensor for detecting platelet-derived growth factor-BB based on isothermal target-triggering strand displacement amplification. Sensors and Actuators B: Chemical. 2015, 207, 748-755.

7. Huige Zhang, Liang Peng, Maoxing Li, Ji Ma, Shengda Qi, Hongli Chen, Lei Zhou, Xingguo Chen. A label-free colorimetric biosensor for sensitive detection of vascular endothelial growth factor-165. Analyst, 2017, 142, 2419-2425.

8. Huige Zhang, Li-juan Wang, Lili Wang, Hongli Chen, Xingguo Chen, Chun-yang Zhang. Development of a cascade isothermal amplification approach for the sensitive detection of DNA methyltransferase. Journal of Materials Chemistry B, 2019, 7, 157-162.

9. Huige Zhang, Lili Wang, Yi Xie, Hongli Chen, Xingguo Chen. Base excision repair mediated cascading triple-signal amplification for the sensitive detection of human alkyladenine DNA glycosylase. Analyst, 2017, 142, 2419-2425.

10. Lili Wang, Huige Zhang, Yi Xie, Hongli Chen, Cuiling Ren, Xingguo Chen. Targetmediated hyperbranched amplification for sensitive detection of human alkyladenine DNA glycosylase from HeLa cells. Talanta, 2019, 194, 846-851.

11. Xianwei Zuo, Huige Zhang, Qian zhu, Weifeng Wang, Jie Feng, Xingguo Chen. A dual-color fluorescent biosensing platform based on WS2 nanosheet for detection of Hg2+ and Ag+. Biosensors and Bioelectronics, 2016, 85, 464-470.

12. Xianwei Zuo, Hongxia Dai, Huige Zhang, Juanjuan Liu, Sudai Ma, Xingguo Chen. A peptide-WS2 nanosheet based biosensing platform for determination of β-secretase and screening of its inhibitors. Analyst, 2018, 143, 4585-4591.


讲授生命科学学院本科生分析化学课程,承担物理化学实验、仪器分析实验的实验课程教学工作。