联系方式

职  称:教授

所在部门:高分子科学与工程研究所

研究方向:生物医用高分子材料;疫苗佐剂

办 公 室 :第一化学楼2024

联系电话:

电子邮件:zhaogh@lzu.edu.cn

赵光辉,教授,博士生导师。2005年6月毕业于兰州大学生命科学学院,获理学学士学位。2005年8月--2011年6月在兰州大学化学化工学院攻读硕士博士学位,师从李彦锋教授。2011年至今在兰州大学化学化工学院从事高分子化学与物理教学和科研工作,2022年被聘为教授、博士生导师。目前主要的研究工作是生物医用高分子和纳米材料的设计合成,围绕创伤修复和抗菌抗病毒,重点开展创伤修复材料、止血材料、抗菌材料以及疫苗佐剂的研究。现主持或已结题的项目有:国家自然科学基金面上项目,国家自然科学基金青年基金、甘肃省重点研发计划、中央高校自由探索基金、国家重点实验室开放基金,横向课题等多项科研项目。近年来,在Adv. Funct. Mater., ACS Appl. Mater. Interfaces, Chem. Commun., J. Phys. Chem.C, Chem. Asian. J, J. Mater. Chem. 等刊物上已发表论文二十余篇。

1、甘肃省重点研发计划:抗细菌生物膜感染智能纳米药物的研发,2021.10-2023.09。

2、国家自然科学基金面上项目:肿瘤细胞内可顺次诱导激活的肉桂醛基功能有机分子的合成、组装及其抗肿瘤研究,2018.01.01-2021.12.31。

3、国家自然科学基金青年基金项目:智能型“酶-抗癌前药”联合传输多功能介孔纳米载药系统的构建及评价,2014.01.01-2016.12.31。


近5年代表性论文(Representative Publications):

1. Shi, Yuting; Yu, Wenwen; Liang, Xiaoqin; Cheng, Ju; Cao, Yufei; Liu, Mingsheng; Fang, Yu; Yang, Zheng; Liu, Hongbin; Wei, Hua;  Guanghui Zhao*. Interpenetrating network expansion sponge based on chitosan and plasma for ultrafast hemostasis of arterial bleeding wounds, Carbohydrate Polymers, 2023, 307, 120590.

2. Shi, Yuting; Cao, Yufei; Cheng, Ju; Yu, Wenwen; Liu, Mingsheng; Yin, Juanjuan; Huang, Congshu; Liang, Xiaoqin; Zhou, Haicun; Liu, Hongbin; Yang, Zheng; Fang, Yu; Wei, Hua;  Guanghui Zhao*; Construction of Self-activated Nanoreactors for Cascade Catalytic Anti-biofilm Therapy Based on H2O2 Self-Generation and Switch-on NO Release, Advanced Functional Materials, 2022: 2111148.

3. Cui, Haiyan; Liu, Mingsheng; Yu, Wenwen; Cao, Yufei; Zhou, Haicun; Yin, Juanjuan; Liu, Hongbin; Que, Sheng; Wang, Jingjing; Huang, Congshu; Gong, Chenliang;  Guanghui Zhao*; Copper Peroxide-Loaded Gelatin Sponges for Wound Dressings with Antimicrobial and Accelerating Healing Properties, ACS Applied Materials & Interfaces, 2021, 13(23): 26800-26807.

4. Yufei Cao, Mingsheng Liu, Ju Cheng, Juanjuan Yin, Congshu Huang, Haiyan Cui, Xiangdong Zhang, and Guanghui Zhao*. Acidity-Triggered Tumor-Targeted Nanosystem for Synergistic Therapy via a Cascade of ROS Generation and NO Release. ACS Applied Materials & Interfaces, 2020, 12, 28975−28984.

5. Tingting Luan, Lulu Cheng, Ju Cheng, Xiaoyun Zhang, Yufei Cao, Xiangdong Zhang, Haiyan Cui, and Guanghui Zhao*. Tailored Design of an ROS-Responsive Drug Release Platform for Enhanced Tumor Therapy via “Sequential Induced Activation Processes”. ACS Applied Materials & Interfaces, 2019, 11, 25654−25663.

6. Lulu Cheng, Tingting Luan, Di Liu, Ju Cheng, Hongping Li, Hua Wei, Lifen Zhang, Jingfeng Lan, Yali Liuc and Guanghui Zhao*. Diblock copolymer glyco-nanomicelles constructed by a maltoheptaose-based amphiphile for reduction- and pH-mediated intracellular drug delivery. Polymer Chemistry, 2018, 9, 1337–1347.

7. Yuting Shi, Hongping Li, Ju Cheng, Tingting Luan, Di Liu, Yufei Cao, Hua Wei, Yali Liu and Guanghui Zhao*. Entirely Oligosaccharide–based Supramolecular Amphiphiles Constructed via Host–guest Interactions as Efficient Drug Delivery Platforms. Chemical Communications, 2017, 53, 12302−12305.

8. Suli Chen, Sidi Zhang, Tao Jin, Guanghui Zhao*. Synthesis and Characterization of Novel Covalently Linked Waterborne Polyurethane/Fe3O4 Nanocomposite Films With Superior Magnetic, Conductive Properties and High Latex Storage Stability. Chemical Engineering Journal, 2016, 286, 249-258.

9. Guanghui Zhao*, Xiaomen Peng, Hongping Li, Jianzhi Wang, Lincheng Zhou, Tianqi Zhao and Haifei Jiang. A Novel Structural Fenton-Like Nanocatalyst with Highly Improved Catalytic Performance for Generalized Preparation of Iron Oxides@Organic Dye Polymer Core-Shell Nanospheres. Chemical Communications, 2015, 51, 7489-7492.


1、代课情况

讲授本科生课程:《高分子基础》、《生物医用材料》、《化学与社会》、《基础化学实验》。

2、教学获奖2017年度甘肃省优秀硕士学位论文指导教师、第十三届“挑战杯”甘肃省大学生课外学术作品优秀指导教师、2015年化学化工学院第二届青年教师讲课比赛三等奖。