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肖建喜(教授)★

【来源:兰州大学化学化工学院 | 发布日期:2018-07-16 】     【选择字号:

 

姓  名
 肖建喜
所属部门
分析化学
职  称
教授
导师类别
博士生导师
研究方向
  生物分析化学,蛋白质化学
联系方式
                    xiaojx@lzu.edu.cn

 

肖建喜,兰州大学化学化工学院教授,博士生导师。兰州大学萃英人才建设计划引进人才,中国分析测试协会青年学术委员会委员,甘肃省化学会青年学术委员会委员。2003年获武汉大学化学学士学位,2009年获美国新泽西州罗格斯大学(Rutgers-New Brunswick)化学博士学位。2009-2011年在罗格斯大学从事博士后研究工作。201212月获聘为兰州大学教授。目前主持国家自然科学基金面上项目,功能有机分子化学国家重点实验室开放基金等多个项目。主要研究领域包括生命分析化学,肿瘤的早期检测,生物仿生材料,胶原蛋白的结构、功能与应用等。在Journal of the American Chemical Society, Chemical Communications, Chemistry-A European Journal, Journal of Biological Chemistry, Journal of Materials Chemistry B等学术期刊发表论文30余篇。论文成果多次被评为热点论文,并被ChemistryViews等国际专业媒体报道。

 

非常欢迎热爱科研的化学、生物学、医学的研究生和本科生加入我们。

 

代表性论文:

1)        X. Cai, Z. Liu, S. Zhao, C. Song, S. Dong and J. Xiao*. A single stranded fluorescent peptide probe for targeting collagen in connective tissues. Chemical Communications, 2017, 53, 11905-11908.

2)        X. Sun, J. Fan, C. Fu, L. Yao, S. Zhao, J. Wang and J. Xiao*. WS2?and MoS2?biosensing platforms using peptides as probe biomolecules. Scientific Reports, 2017, 7, 10290.

3)        M. He, Y. Zhang, J. Munyemana, T. Wu, Z. YangH. Chen, W. Qu, and J. Xiao*. Tuning the hierarrchical nanostructure of hematite mesocrystals by collagen-templated biomineralization. Journal of Materials Chemistry B, 2017, 5, 1423-1429.

4)        M. He, L. Wang, J. Wu and J. Xiao*. Ln3+-Mediated Self-Assembly of a Collagen Peptide into Luminescent Banded Helical Nanoropes. Chemistry - A European Journal, 2016, 22, 1914-1917. (Hot paper)

5)        X. Sun, J. Fan, W. Ye, H. Zhang, Y. Cong and J. Xiao*. A Highly Specific Graphene Platform for Sensing Collagen Triple Helix. Journal of Materials Chemistry B, 2016, 4, 1064-1069. (Hot paper)

6)        X. Cai, Q. Yang, J. Ding, W. Ye, X. Li, and J. Xiao*. Paper-based FRET for direct detection of collagen triple helix. Journal of Materials Chemistry B, 2016, 4, 7009-7013.

7)        X. Sun, J. Fan, X. Li, S. Zhang, X. Liu and J. Xiao*. Colorimetric and Fluorometric Monitoring of the Helix Composition of Collagen Peptides at nM level. Chemical Communications, 2016, 52, 3107-3110.

8)        X. Sun, J. Fan, Y. Zhang, H. Chen, Y. Zhao and J. Xiao*. A graphene oxide-based FRET sensor for rapid and specific detection of unfolded collagen fragments. Biosensors and Bioelectronics, 2016, 79, 15-21.

9)        J. Xiao, X. Sun, M. Balaram, B. Brodsky and J. Baum. NMR Studies Demonstrate a Unique AAB Composition and Chain Register for a Heterotrimeric Type IV Collagen Model Peptide Containing a Natural Interruption Site. Journal of Biological Chemistry, 2015, 90, 24201-24209.

10)    J. Xiao, R.M. Addabbo, J.L. Lauer, G.B. Fields, and J. Baum. Local conformation and dynamics of isoleucine in the collagenase cleavage site provides recognition signal for matrix metalloproteinases. Journal of Biological Chemistry, 2010, 285, 34181.

11)    J. Xiao and J. Baum. Structural insights from 15N relaxation data for an anisotropic collagen peptide. Journal of the American Chemical Society, 2009, 131, 18194.

12)    M. Balaraman, J. Xiao, G. Thiagarajan, J. Baum and B. Brodsky. NMR monitoring of chain-specific stability in heterotrimeric collagen peptides. Journal of the American Chemical Society 2008, 130, 13520.