联系方式

职  称:教授

所在部门:有机化学第五研究所

研究方向:天然产物全合成及生物合成途径研究、全合成导向的有机合成方法学研究以及药物化学研究

办 公 室 :

联系电话:

电子邮件:yangming@lzu.edu.cn

阳铭,19873月生于湖北潜江,理学博士,兰州大学萃英特聘教授,博士生导师。20086月毕业于湖北大学化学化工学院化学(师范类)专业,20136月获兰州大学有机化学专业理学博士学位,师从涂永强院士。20138月至201511月,在中国科学院上海有机化学研究所李昂研究员课题组从事博士后研究。201512月至201812月,在芝加哥大学Scott A. Snyder教授课题组从事博士后研究。20191月至今,在兰州大学化学化工学院、功能有机分子化学国家重点实验室从事教学科研工作。主要研究方向为具有重要生物活性的复杂天然产物全合成、有机合成方法学与药物化学。自独立建组之后完成了个复杂天然产物的全合成,以通讯作者在J. Am. Chem. Soc.Angew. Chem. Int. Ed.Nat. Commun.等国际知名期刊发表多篇学术论文。2023年荣获Thieme Chemistry Journals AwardAsian Core Program Lectureship Award (from Japan),并于同年获得国家自然科学基金委优秀青年科学基金资助。


近期代表性论文:

1. Du, Q.; Fan, Z.; Yang, M.* Total Synthesis of Principinol B. Angew. Chem. Int. Ed. 2024, 63, e202400956.

2. Zhao, W.; Zhang, D.; Wang, Y.; Yang, M.* Total Syntheses of Rhodomollins A and B. J. Am. Chem. Soc. 2023, 145, 27160. (Featured in ChemistryViews; Feattured in Synfacts 2024, 20, 225.)

3. Gong, X.; Huang, J.; Sun, X.; Chen Z.; Yang, M.* Total Synthesis of Illisimonin A and Merrilactone A. Angew. Chem. Int. Ed. 2023, 62, e202306367. (G.X., H.J. and S.X. contributed equally.)

4. Zhu, W.; Yin, Q.; Lou, Z.; Yang, M.* Modular Total Syntheses of trans-Clerodanes and Sesquiterpene (Hydro)quinones via Tail-to-Head Cyclization and Reductive Coupling Strategies. Nat. Commun. 2022, 13, 6633. (Z.W. and Y.Q. contributed equally; Featured in Org. Chem. Highlights. )

5. Wang, Y.; Zhao, R.; Yang, M.* Total Synthesis of Mollanol A. J. Am. Chem. Soc. 2022, 144, 15033. (W.Y. and Z.R. contributed equally; featured in Synfacts 2022, 18, 1169; selected by editors as “Synfact of the Month”.)

6. Yang, M.; Yin, F.; Fujino, H.; Snyder, S. A.* The Total Synthesis of Chalcitrin. J. Am. Chem. Soc. 2019, 141, 4515. (Featured in Synfacts 2019, 15, 0587; Featured in Org. Chem. Highlights; Featured in ChemistryViews)

7. Yang, M.; Yang, X.; Sun, H.; Li A.* Total Synthesis of Ileabethoxazole, Pseudopteroxazole, and seco-Pseudopteroxazole. Angew. Chem. Int. Ed. 2016, 55, 2851. (Very Important Papers in Angew. Chem. Int. Ed.; featured in Synfacts 2016, 12, 329; selected by editors as “Synfact of the Month”; Featured in Org. Chem. Highlights.)

8. Yang, M.; Li, J.; Li, A.* Total Synthesis of Clostrubin. Nat. Commun. 2015, 6, 6445.

9. Lu, Z.; Yang, M.; Chen, P.; Xiong, X.; Li, A.* Total Synthesis of Hapalindole-Type Natural Products. Angew. Chem. Int. Ed. 2014, 53, 13840. (L.Z. and Y.M. contributed equally; featured in Synfacts 2015, 11, 1; selected by editors as “Synfact of the Month”.)